House is injured in a motorcycle accident in New York and finds himself in bed next to a patient suffering from complete paralysis. As House transfers the patient to Princeton to determine what’s wrong with him, Wilson tries to find out why House was in New York.
The heroes try to mend their broken relationships as Nathan and Claire seek refuge in Mexico and Peter and Angela hide out in a church. Danko’s bid to wipe out the superpowered population intensifies as he unites with a surprising new ally.
Everyone on the island is at risk when one of the survivors decides to go against them and take matters into their own hands.
Chloe discovers how the other half lives when she wishes for a peaceful life like her cousin Lois… and a sorceress transforms her into Lois. Meanwhile, Clark receives a wish of his own.
The identity of “Rebel” is revealed. Noah wants Danko to let Tracy go in the hope that she will lead them to Rebel. Hiro and Ando continue with the mission that Rebel entrusted to them, to keep the new hero safe.
Tess Mercer invites Clark to accompany her to a press conference in Los Angeles, but when an accident cripples the plane, Clark must choose between saving Tess and revealing his powers, or letting her die. Meanwhile, Davis tries to control the Doomsday monster within.
After meeting old acquaintances Sawyer is forced to continue lying to protect them.
A nursing home worker, Morgan, fakes an illness to get House to examine a cat which can predict the death of elderly patients. House doesn’t believe it… until Morgan becomes ill for real.
When Clark’s secret identity as the “Red-Blue Blur” is threatened, he decides to go public by having Lois publish his story. However, he soon discovers the price that goes with public fame.
Sylar finds his father at last, Claire must decide whether to help a sworn enemy, Danko digs into the secrets of the Petrelli family, and Matt must find a way out of an explosive situation.
